This card is a little weird, and it is best compared to another similar card, Mind over Matter.
For 1 resource you drop a foe's combat and evade rating by 2, this is a much stronger effect than increasing your own chances by the same value because: When you attempt a skill test, the result cannot go under 0. I.E, if you encounter foes that have 2 or less evade and fight values, evading or fighting them becomes pretty trivial once you drop those number's to 0. Swarm of Rats become autokill's for example, and so do Ghoul Minion if you just got the two actions.
So why isn't this autotake? I'll tell you, it's not just because of the severe drawback listed in it's play conditions. Against a foe that is harder to hit or Evade than just 2, you Immediately need to start backing up your tests with some actual stats, dropping a foe to 1 fight for example so that you can throw your Str of 2 at isn't that much better on, say, Hard difficulty. You'll need some other way to boost the attempt.
There is another upside to this card. Playing it to buff an actual combat character is a huuuuge play, especially if you're trying to kill some kind of boss, a -2 difficulty on every attack for 2 or 3 attacks is going to stack up a lot of extra hits
So, the comparison. Mind over Matter does a similar thing, but it's not limited by Sanity, and it's not team friendly, a fair trade-off because for character's the net benefit is mostly the same, usually a gain of +2 or more or , with Dr. Milan Christopher the gain can be enhanced. Dont forget that a isnt likely to have perennial support cards like Overpower, meanwhile Mind over Matter enables the use of Perception and the like to pump your fight value.
So, IF you do intend to take your brainiac out to punch some fools, this card is probably a bit better than Mind over Matter because of it's team utility and it's enhanced efficiency against low difficulty threats (Which can be an issue for pacifist characters to deal with), but if you actually intend to crunch some heads with your superb intellect then Mind over Matter is more reliably going to help you score hits on harder foes.
Edit: I'm a huge fan of equipping Norman Withers with Knife / Enchanted Blade, this card and Mind over Matter. One of the problems with combo cards like this one is actually finding it early enough to be in your hand when the circumstance arises. Norman speeds through a deck and can assemble all of those pieces faster than anybody else, also Anatomical Diagrams lets him autokill his weakness (barring autofail tokens).