This looks fantastic for Minh Thi Phan with Analytical Mind.
Not only is Minh more likely to interpret the dreams successfully over the course of a scenario (with the need to over-commit for The King in Yellow), Minh can effectively give a +2-5 (possibly +6/7 with Grisly Totem (3)) boost to any skill test for any investigator each round, with greater flexibility over turn order as well as the option to save it for the next round.
With Dream-Enhancing Serum, Minh should easily be able to reach and hold 8+ cards in her hand each round.
Unfortunately, it will take up one of her hand slots which is generally reserved for Ancient Stone (4) and The King in Yellow, albeit the latter being involuntary.
I can also see this doing well in a Daisy Walker deck.
Any other suggestions on who else it would be good with?