Four years on and Synisill's review is still all relevant in almost all cases, but there are two new investigators that can squeeze a little extra use out of poor, poor Aquinnah.

It takes some luck or surgical card draw, but Aquinnah can turn off Patrice Hathaway's signature weakness. The Watcher from Another Dimension is an enemy that attacks you, it just does it from your hand; thus, she can reflect the 3 damage onto an enemy at your location. The significant caveat is that you'd have to save up the whopping 5 resources and have it available during the window when she flies through your hand to play her. You'd also likely need some form of deck manipulation to make sure your deck runs out only when there's an enemy at your location, or else the reflect fails and you still take the hit. Her expensive upgrade makes her $1 cheaper, but her upgraded ability is a bit wasted because you can't reflect it back at the Watcher itself. You may fight or evade the Watcher as though it were at your location, but it's not actually at your location for other effects, such as Aquinnah's ; it's still considered to be in your hand.

More relevant is new kid on the block Daniela Reyes, whose entire schtick is goading enemy attacks. She synergizes with Counterpunch, Toe to Toe, Fend Off and the Bangle of Jinxes. Useful for dealing with enemies you don't want to engage, like the Innsmouth spoiler or Innsmouth spoiler, or enemies that are just plain annoying like everyone's favorite bird. Of course, she's still $5 and still competes for a slot against the perennially useful Peter Sylvestre, but there's always Charisma and Calling in Favors.

Could I use the bold printed "Fight." on "Get over here!" to trigger fight action on for example a weapon asset in play (Machete) I assume not. Just a question that came up in a latest round. ..................

I can maybe... maybe... see this card in a heavy-soak deck. (Non-Ally soak, to be more precise.) The problem is, it costs one card and a resource to play, so it's really only cost-efficient if you're taking three damage/horror at a time, something that most players try to avoid. Well, if money isn't an issue, you get a net benefit at 2 damage/horror, but nonetheless, it's hard to justify taking. It would be a good but niche card at 0 XP. I can't see it being worth 2 XP.

At level 0, Father Mateo now has access to Spectral Razor, which will put him up 6 to 2, which should be good on most campaigns on Standard, and will do the 3 damage necessary to take care of this on one action. And since you have a built-in way to deal with the Auto-Fail token, these snakes aren't so difficult to deal with.

Is... Is that Taylor Swift in the art?

As much as I like Panic, Stupor, and Arm/Leg Injury from a mechanics perspective, they feel both flavorful and balanced, I feel like running an all soak no healing style deck hamstrings anyone that happens to pull one of these as a random weakness.

Barring something like Doomed or Offer You Cannot Refuse or maybe Through the Gates hitting something important, I feel like most basic weaknesses can be dealt with by anyone... even if it's devastating to the bearer (like Drawing the Sign with Harvey Walters or Paranoia in a big money deck). Harvey probably isn't happy to see Drawing the Sign pop out, but he can still toss it and move on rebuilding his hand. But if you happen to be running someone like Tommy Muldoon relying almost entirely on asset soak instead of healing getting one of these weaknesses cripples you from the moment you draw it to the end of that scenario. In my opinion how you feel about these weaknesses entirely depends on what kind of deck you're playing when you get them. Getting Panic or Stupor in a Carolyn deck probably doesn't bother you (I assume that since you can heal it as if it was horror it would still trigger her ability) as you can just treat it as "Miss a draw, take 1 fake horror, and maybe have to restructure your next turn or two if you're unlucky" but a soak heavy no healing Tommy deck likely has to pick up a new card to compensate for the newfound gaping wound in their arm, leg, or psyche.

Thematically these weaknesses are very flavorful and mechanically interesting, I just wouldn't want to be stuck in the middle of the Antarctic without a Medical Student or First Aid kit. Peter Sylvestre and Jessica Hyde just have to sit there and watch you bleed and panic since the "horror" or "damage" is on you, not them.