This card seems to be worth one or two off-class slots in Jim Culver and Dr. Elli Horowitz relic-focused deck, for cracking monsters' heads with empty Flashlight, Enchanted Blade, Grotesque Statue, surplus The Chthonian Stone, or, of course, for maximum style points, the Jim's Trumpet itself, reenacting the "And now, the drum solo!" scene from Futurama: www.youtube.com

With Makeshift Trap (Improved Timer. + Net.) and some other tricks (Lure/Lure, Bait and Switch, "Get over here!"/"Get over here!", Predator or Prey) you can have your own antimatter singularity for 6 less XP than the boring vanilla Poisonous. + Explosive Device. combo.

Probably still only worth it in Calvin, but this way I think you can truly maximize the output of "I'll see you in hell!".

(I guess it's also viable in Tommy since he can easily take the trauma.)

Besides the obvious curse synergies, this is a great card for the low-/zero-difficulty playstyle, using Makeshift Trap, Gumption, and Oops!/Oops!.

You can also pair it with Justify the Means, Three Aces, or, if you do care about the curses, drop a Favor of the Moon in the player window during the skill test.

Thinking of Preston Fairmont.

Norman Withers and The Harbinger say hi. While not game-breaking, the interactions between empty space and this investigator can lead to interesting and unique edge (of the universe) cases.

Wake Azathoth, they said. It will be fun, they said.

2x Ariadne's Twine 1x Cryptic Grimoire 1x Dr. Milan Christopher

Congratulations, now you get 1 actionless Investigate that charges your Myconid every single round. The Myconids seem likely to get Taboo'd pretty quickly to me, especially the Sentient Strain. It is incredibly easy to game these things out and trivialize an entire scenario.